Process Intensification: PAT, AI, ML to Support Intensified Bioprocessing

February 14, 2023

Arthi Narayanan, innovation team leader of pharma technical operations at Genentech, and John Bonham-Carter, board member and VP of business development and product management at Erbi Biosystems, discuss how process analytical technology, artificial intelligence, and machine learning support intensified bioprocessing and improve inefficiencies. Narayanan talks about the expected outcomes predictive modeling will likely produce in the coming years, why data is the “power” of bioprocessing, and how to leverage predictive modeling to accelerate tech transfer. She also discusses the importance of accepting and trusting new technologies, the mindset surrounding data and employee acquisition that often leads to success, and how to manage workforce integration.

GUEST BIO

Arthi Narayanan, Innovation Team Leader of Pharma Technical Operations, Genentech
Arthi Narayanan currently serves as an innovation senior team leader for pharma technical operations at Roche-Genentech USA. Narayanan brings over 20+ years of biopharma industry experience in varying capacities within process development and manufacturing. She is currently leading a team of multi-disciplinary engineers focused on developing and implementing end-to-end next-generation technological solutions to deliver medicines to patients smarter, better, and faster.

MODERATOR BIO

John Bonham-Carter, Board Member and VP of Business Development and Product Management, Erbi Biosystems
John Bonham-Carter is recognized as one of the early pioneers in making continuous bioprocessing a manufacturing reality. Leveraging the ATF System technology developed at Refine Technology (acquired by Repligen in 2014), Bonham-Carter helped forge the future of intensified processing, ensuring that all processes could benefit from exceptionally high productivity processes. To date, 20+ therapeutic products, from vaccines to gene therapies and proteins, are now commercially manufactured with products that Bonham-Carter brought to market. He is sought after as a technically focused expert to bring new technologies to market and has been a regular international speaker and co-organizer of several cell culture conferences.